abstract：:The polarization of macrophages and its anti-inflammatory and proinflammatory properties play a significant role in host response after implant placement to determine the outcome of osseointegration and long-term survival. In the previous study, we immobilized an antimicrobial peptide, GL13K, onto titanium surfaces to...

journal_title：BioMed research international

authors： Chen X,Zhou L,Wu D,Huang W,Lin Y,Zhou B,Chen J

更新日期：2020-07-24 00:00:00

abstract：:Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn disease (CD). Similar symptoms, but different treatment procedures for both diseases require precise diagnosis. MicroRNAs (miRNAs) are major posttranscriptional players that regulate the expression of genes during the inflammation and thus co...

journal_title：BioMed research international

authors： Guz M,Dworzański T,Jeleniewicz W,Cybulski M,Kozicka J,Stepulak A,Celiński K

更新日期：2020-07-22 00:00:00

abstract：Introduction:To identify and analyze factors that influence administration, recognition, and compliance of medicine among community residents in Jilin Province, China. Methods:A survey was carried out among 2417 community residents in Jilin Province, China, to study their administration (CRA), recognition (CRR), and c...

journal_title：BioMed research international

authors： Song YQ,Zhang WR,Zhang SX,Wang TH,Jiang Z,Meng CF,Zhang TZ,Xin QZ,Cao KJ,Zhang Y,Sun Y

更新日期：2020-07-18 00:00:00

abstract：:The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with major abnormalities of hepatic lipid metabolism. We propose that lipid abnormalities directly or indirectly contribute to NAFLD, especially fatty acid accumulation, arachidonic acid metabolic disturbance, and ceramide overload. The effects o...

journal_title：BioMed research international

authors： Pei K,Gui T,Kan D,Feng H,Jin Y,Yang Y,Zhang Q,Du Z,Gai Z,Wu J,Li Y

更新日期：2020-07-18 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2019/4370258.]. ...

journal_title：BioMed research international

authors： Yaradua SS,Alzahrani DA,Albokhary EJ,Abba A,Bello A

更新日期：2020-07-16 00:00:00

abstract：Background:Uveitis is a known ophthalmologic manifestation of seronegative spondyloarthropathy, including psoriatic arthritis. However, the data is less clear among patients with psoriasis due to the limited number of published studies. Aims:To investigate whether the risk of incident and prevalent uveitis is elevated...

journal_title：BioMed research international

authors： Chaiyabutr C,Ungprasert P,Silpa-Archa N,Wongpraparut C,Chularojanamontri L

更新日期：2020-07-15 00:00:00

abstract：:The main aim was to analyse the associations between several physical fitness variables and bone parameters in a sample of elderly people. 129 participants (94 females and 35 males, 76.2 ± 5.4 y) from the EXERNET cohort of Zaragoza (Spain) were included in the study. Physical fitness was assessed using the Senior Fitn...

journal_title：BioMed research international

authors： Moradell A,Gómez-Cabello A,Gómez-Bruton A,Muniz-Pardos B,Puyalto JM,Matute-Llorente A,Gónzalez-Agüero A,Ara I,Casajús JA,Vicente-Rodríguez G

更新日期：2020-07-15 00:00:00

abstract：:This study is aimed at determining how oral squamous cell carcinoma (OSCC) regulates the angiogenesis of HUVECs through miR-210-3p expression and exploring the relationship among miR-210-3p, its target protein, and the possible mechanism of angiogenesis regulation. miR-210-3p expression was detected in OSCC tissues an...

journal_title：BioMed research international

authors： Wang H,Wang L,Zhou X,Luo X,Liu K,Jiang E,Chen Y,Shao Z,Shang Z

更新日期：2020-07-08 00:00:00

abstract：:Exosomes can reach distant tissues through blood circulation to communicate directly with target cells and rapidly regulate intracellular signals. Exosomes play an important role in cardiovascular pathophysiology. Different exosomes derived from different sources, and their cargos have different mechanisms of action. ...

journal_title：BioMed research international

authors： Liang B,He X,Zhao YX,Zhang XX,Gu N

更新日期：2020-07-07 00:00:00

abstract：:Spontaneous bacterial peritonitis (SBP) is a common cirrhotic ascites complication which exacerbates the patient's condition. SBP is caused by gram-negative bacilli and, to a lesser extent, gram-positive cocci. Hospital-acquired infections show higher levels of drug-resistant bacteria. Geographical location influences...

journal_title：BioMed research international

authors： Li YT,Huang JR,Peng ML

更新日期：2020-07-06 00:00:00

abstract：Objective:Multifocality within an affected lobe (unilateral multifocality) or two lobes (bilaterality) is commonly denoted as multifocality without differentiation. Recently, there has been molecular evidence indicating that unilateral multifocality and bilaterality could be two different entities. However, few studies...

journal_title：BioMed research international

authors： Cai J,Fang F,Chen J,Xiang D

更新日期：2020-07-03 00:00:00

abstract：Background:Pyroptosis, a novel form of inflammatory programmed cell death, was recently found to be a cause of mucosal barrier defect. In our pervious study, CD147 expression was documented to increase in intestinal tissue of inflammatory bowel disease (IBD). Objective:The aim of this study was to determine the functi...

journal_title：BioMed research international

authors： Xu Z,Liu R,Huang L,Xu Y,Su M,Chen J,Geng L,Xu W,Gong S

更新日期：2020-06-30 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2020/4671349.]. ...

journal_title：BioMed research international

authors： Dhahri H,Rahmany I,Mahmood A,Al Maghayreh E,Elkilani W

更新日期：2020-06-30 00:00:00

abstract：:Non-small-cell lung cancer (NSCLC) patients often develop bone metastases (BM), and the overall survival for these patients is usually perishing. However, a model with high accuracy for predicting the survival of NSCLC with BM is still lacking. Here, we aimed to establish a model based on artificial intelligence for p...

journal_title：BioMed research international

authors： Huang Z,Hu C,Chi C,Jiang Z,Tong Y,Zhao C

更新日期：2020-06-27 00:00:00

abstract：:Growing evidence indicates that immune-related biomarkers play an important role in tumor processes. This study investigates immune-related gene expression and its prognostic value in lung squamous cell carcinoma (LUSC). A cohort of 493 samples of patients with LUSC was collected and analyzed from data generated by th...

journal_title：BioMed research international

authors： Yan Y,Zhang M,Xu S,Xu S

更新日期：2020-06-27 00:00:00

abstract：:The hallucal sesamoid bones (HSBs), having an important role in reducing load per unit area on the first metatarsal head, can be injured commonly which also affected the first metatarsophalangeal joint and the surrounding structure. Meanwhile, differences among each HSB type may be a major factor affecting the occurre...

journal_title：BioMed research international

authors： Zhang L,Wang J,Liu J,Luo J

更新日期：2020-06-26 00:00:00

abstract：Results:In 221 cycles from 138 patients (104 cycles requiring HLA matching), 90.5% had embryo(s) biopsied for genetic testing. There were 119 embryo transfers for thalassemia (76) and thalassemia-HLA cases (43), respectively, resulting in overall clinical pregnancy rates of 54.6%, implantation rates of 45.7%, and live ...

journal_title：BioMed research international

authors： Tiewsiri K,Manipalviratn S,Sutheesophon W,Vanichsetakul P,Thaijaroen P,Ketcharoon P,Bradley CK,McArthur SJ,Krutsawad W,Marshall JTA,Papadopoulos KI

更新日期：2020-06-26 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2020/5901962.]. ...

journal_title：BioMed research international

authors： Hsu CC,Ko JY,Lin CL,Hsu HC,Chen HT,Lin CC,Kuo SJ

更新日期：2020-06-22 00:00:00

abstract：Background:The Oxford Happiness Inventory (OHI) is a self-report tool to measure happiness. A brief review of previous studies on OHI showed the lack of evaluation of OHI fairness/equivalence in measuring happiness among identified groups. Methods:To examine the psychometric properties and measurement invariance of th...

journal_title：BioMed research international

authors： Mousavi A,Sharafi Z,Mahmoudi A,Shahraki HR

更新日期：2020-06-21 00:00:00

abstract：Objective:The aim of this study was to investigate the association between adiponectin gene polymorphisms rs10937273, rs1501299, rs182052, rs2241767, and rs266729 and environmental risk factors of type 2 diabetes mellitus (T2DM) in Hohhot. The study explored different models of gene-environment interactions, aimed at p...

journal_title：BioMed research international

authors： Cui M,Gao Y,Zhao Y,Pang H,Chen L,Wang Z,Zhao L,Li M

更新日期：2020-06-21 00:00:00

abstract：:During a spaceflight, astronauts need to live in a spacecraft on orbit for a long time, and the relationship between humans and microorganisms in the closed environment of space is not the same as on the ground. The dynamic study of microorganisms in confined space shows that with the extension of the isolation time, ...

journal_title：BioMed research international

authors： Chen Y,Wu B,Zhang C,Fan Z,Chen Y,Xin B,Xie Q

更新日期：2020-06-20 00:00:00

abstract：:Atherosclerosis remains the most common cause of deaths worldwide. Endothelial cell apoptosis is an important process in the progress of atherosclerosis, as it can cause the endothelium to lose their capability in regulating the lipid homeostasis, inflammation, and immunity. Endothelial cell injury can disrupt the int...

journal_title：BioMed research international

authors： Song N,Jia L,Cao H,Ma Y,Chen N,Chen S,Lv X,Yang G

更新日期：2020-06-20 00:00:00

abstract：:Persistent catecholamine-resistant shock in children causes severe morbidity and mortality. We aimed to analyze the association between hemodynamics and serum lactate at different time points and 28-day mortality in children with persistent catecholamine-resistant shock. Methods. Twenty-six children with persistent ca...

journal_title：BioMed research international

authors： Lee EP,Chu SC,Hsia SH,Chen KF,Chan OW,Lin CY,Su YT,Lin JJ,Wu HP

更新日期：2020-06-19 00:00:00

abstract：:Purslane, a fleshy herbaceous plant, plays a pivotal role in various preventive and therapeutic purposes. To date, no report has documented the consequence of salt stress on metabolite accumulation in purslane. Herein, we proposed an insight into the metabolic and physiological traits of purslane under saline stress e...

journal_title：BioMed research international

authors： Zaman S,Bilal M,Du H,Che S

更新日期：2020-06-17 00:00:00

abstract：Background:Sympathetic sprouting in the dorsal root ganglion (DRG) following nerve injuries had been proved to induce adult neuropathic pain. However, it is unclear whether the abnormal sprouting occurs in infant nerve injury. Methods:L5 spinal nerve ligation (SNL) or sham surgery was performed on adult rats and 10-da...

journal_title：BioMed research international

authors： Liu P,Zhang Q,Gao YS,Huang YG,Gao J,Zhang CQ

更新日期：2020-06-16 00:00:00

abstract：:Vitamin D and its cognate intracellular nuclear receptor, namely, vitamin D receptor (VDR), are involved in the regulation of a variety of body metabolic processes, immune function, and oncogenesis. A large number of studies demonstrated the association of low vitamin D levels and variations in five common single nucl...

journal_title：BioMed research international

authors： Suksawatamnuay S,Sriphoosanaphan S,Aumpansub P,Aniwan S,Thanapirom K,Tanasanvimon S,Thaimai P,Wiangngoen S,Ponauthai Y,Sumdin S,Angspatt P,Rerknimitr R,Poovorawan Y,Komolmit P

更新日期：2020-06-15 00:00:00

abstract：:Antibiotics are among the most counterfeited anti-infectious medicines in developing countries. Amoxicillin is one of the commonly prescribed, affordable, and easily accessible antibiotic in Kenya. It is a broad-spectrum antibiotic hence commonly used in chemotherapy. This study sought to determine the quality and ide...

journal_title：BioMed research international

authors： Koech LC,Irungu BN,Ng'ang'a MM,Ondicho JM,Keter LK

更新日期：2020-06-12 00:00:00

abstract：Objectives:To evaluate the effects of pentobarbital dosages on lower urinary tract function and to define an appropriate dosage of sodium pentobarbital that would be suitable for urodynamic studies in which recovery from anesthesia and long term survive were needed for subsequent experiment. Methods:Twenty-four 8-week...

journal_title：BioMed research international

authors： Xu SF,Du GH,Abulikim K,Cao P,Tan HB

更新日期：2020-06-11 00:00:00

abstract：Design:From July 2016 to June 2018, 36 women with symptomatic early pregnancy around 4-8 weeks of gestation were recruited into the study. Among them, there were 16 women with viable intrauterine pregnancy (VIP), 9 women with spontaneous abortion (SA), and 11 women of EP. Serum exosomal miRNAs were extracted and measur...

journal_title：BioMed research international

authors： Sun J,Deng G,Ruan X,Chen S,Liao H,Liu X,Li J,Zhao G,Gao J

更新日期：2020-06-11 00:00:00

abstract：Methods:In the study, we included 86 children diagnosed with atopic asthma (n = 25), allergic rhinitis (n = 20), and atopic dermatitis (n = 20) and healthy control subjects (n = 21) of Caucasian origin from the Polish population. The blood leukocyte expression of 31 genes involved in neuroinflammatory response (neurotr...

journal_title：BioMed research international

authors： Sobkowiak P,Langwiński W,Nowakowska J,Wojsyk-Banaszak I,Szczepankiewicz D,Jenerowicz D,Wasilewska E,Bręborowicz A,Szczepankiewicz A

更新日期：2020-06-10 00:00:00

abstract：:Lung cancer is one of the most malignant tumors in the world. Early diagnosis and treatment of lung cancer are vitally important to reduce the mortality of lung cancer patients. In the present study, we attempt to identify the candidate biomarkers for lung cancer by weighted gene co-expression network analysis (WGCNA)...

journal_title：BioMed research international

authors： Xu X,Xu L,Huang H,Li J,Dong S,Jin L,Ma Z,Li L

更新日期：2020-06-10 00:00:00

abstract：Background:A deficiency in steroid 5α-reductase type 2 is an autosomal recessive disorder. Affected individuals manifested ambiguous genitalia, which is caused by decreased dihydrotestosterone (DHT) synthesis in the fetus. Methods:We analyzed 25 patients with 5α-reductase deficiency in China. Seventeen of the 25 patie...

journal_title：BioMed research international

authors： Han B,Cheng T,Zhu H,Yu J,Zhu WJ,Song HD,Yao H,Qiao J

更新日期：2020-06-09 00:00:00

abstract：:The success rate of oral implants is lower in type 2 diabetes mellitus (T2DM) patients than in nondiabetic subjects; functional impairment of bone marrow-derived mesenchymal stem cells (BMSCs) is an important underlying cause. Many factors in the blood can act on BMSCs to regulate their biological functions and influe...

journal_title：BioMed research international

authors： Liang C,Sun R,Xu Y,Geng W,Li J

更新日期：2020-06-07 00:00:00

abstract：Background:The mechanism of inflammatory reaction after intracerebral hemorrhage remains unclear, which to some extent restrains the therapeutic development of hemorrhagic stroke. The present study attempts to verify whether NLRP6 plays an important role in inflammatory reaction after intracerebral hemorrhage and ident...

journal_title：BioMed research international

authors： Nie H,Hu Y,Guo W,Wang W,Yang Q,Dong Q,Tang Y,Li Q,Tang Z

更新日期：2020-06-07 00:00:00

abstract：Background:Preeclampsia (PE) is a pregnancy-specific hypertension syndrome and is one of the leading causes of maternal and perinatal morbidity and mortality. Long noncoding RNAs (lncRNAs) have been reported to be abnormally expressed in many diseases, including preeclampsia. The present study is aimed at identifying t...

journal_title：BioMed research international

authors： Zhang Z,Wang P,Zhang L,Huang C,Gao J,Li Y,Yang B

更新日期：2020-06-05 00:00:00

abstract：Background:Clinical trials based on FGFR mutation or amplification as a druggable target of FGFR inhibitors have produced disappointing clinical outcomes. Therefore, the identification of predictive biomarkers for FGFR-targeted agents has remained a crucial issue. Methods:Expression profiles of FGFs and FGFRs in 8,111...

journal_title：BioMed research international

authors： Li Y,Wu L,Tao W,Wu D,Ma F,Li N

更新日期：2020-06-03 00:00:00

abstract：:SARS-CoV-2 pandemic and COVID-19 diffusion have recently become an international public health emergency. Cancer patients, as a frail population, are particularly exposed to the risk related to infections. The clinical decision-making process and the organizational workflow of radiotherapy department should be revised...

journal_title：BioMed research international

authors： Franco P,Kochbati L,Siano M,De Bari B

更新日期：2020-05-26 00:00:00

abstract：:Synovitis plays an important role in the pathogenesis of arthritis, which is closely related to the joint swell and pain of patients. The purpose of this study was to investigate the anti-inflammatory effects of pulsed electromagnetic fields (PEMF) on synovitis and its underlying mechanisms. Destabilization of the med...

journal_title：BioMed research international

authors： Ouyang J,Zhang B,Kuang L,Yang P,Du X,Qi H,Su N,Jin M,Yang J,Xie Y,Tan Q,Chen H,Chen S,Jiang W,Liu M,Luo X,He M,Ni Z,Chen L

更新日期：2020-05-26 00:00:00

abstract：:Gastric cancer (GC) is one of the most common and fatal malignancies worldwide. MicroRNAs (miRNAs) play a critical role in tumor initiation, proliferation, and metastasis of gastric cancer. miR193b has been identified as a tumor suppressor in a variety of tumor types; however, its role in gastric cancer is yet to be d...

journal_title：BioMed research international

authors： Tian R,Jiang H,Shao L,Yu Y,Guo Q,Cao B,Guo S

更新日期：2020-05-25 00:00:00

abstract：Background:The incidence of osteoporotic fractures is increasing. In this study, we explored the activities of Wnt/β-catenin signaling in bone tissues with iron accumulation. Methods:We established rat bipedal walking models (RBWM), and a portion of our RBWM rats were intraperitoneally injected with ferric ammonium ci...

journal_title：BioMed research international

authors： Xu W,Yu R,Zhu X,Li Z,Jia J,Li D,Chen Y,Zhang X

更新日期：2020-05-24 00:00:00